Sunday, October 28, 2012

Chemistry of lipids

Q.1- Endogenously synthesized triacylglycerols are transported from liver to extra hepatic tissues by which of the followinglipoproteins?
a) Chylomicrons
c) LDL
d) HDL     
Q.2- All of the followings have 18 carbon atoms except –
a) Linoleic acid
b) Palmitic acid
c) Linolenic acid
d) Stearic acid        
Q.3- Sphingosine is not present in-
a) Cerebrosides
b) Gangliosides
c) sphigomyelin
d) Plasmalogen                         
Q.4- Triacylglycerols are-
a) Energy rich compounds
b) Nonpolar in nature
c) Can be stored in unlimited amounts
d) All of the above           
Q.5- All are essential fatty acids except-              
b) Linolenic
c) Arachidonic acid
d) Stearic acid        
Q.6- The deficiency of Lung surfactant, Dipalmitoyllecithin (DPL) causes, Respiratory Distress Syndrome. DPL is a –
a) Cerebroside
b) Ganglioside
c) Phospholipid
d) Lipoprotein
Q.7- Choose the correct statement
a) The melting point of a fatty acid increases with the increasing degree of unsaturation in the hydrophobic chain
b) Most of the naturally fatty acids have trans double bonds
c) Arachidonic acid is a relatively nonessential fatty acid
d) The membrane lipids are rich in saturated fatty acids.
Q.8- Which out of the following fatty acids is a precursor of series -1 Eicosanoids?
a) Linoleic acid
b) Arachidonic acid
c) Eicosapentaenoic acid
d) Linolenic acid
Q.9- What is the cause of hyper acidity on long-term usage of Aspirin?
a) Inhibition of cyclo oxygenase
b) Increased synthesis of PGs
c) Inhibition of Phospholipase A2
d) All of the above
Q.10- Which nitrogenous base out of the followings is present in lecithin —?
b) Adenine
c) Ethanolamine
d) Any of the above
Q.11- Cholesterol is a precursor of all except-
a)Bile salts,
c) Steroids
d) vitamin D                             
Q.12- Glycerol is used for the synthesis of all except-
a) Glucose.,
b) Phospholipids,
c) Glycolipids,
d) Triacylglycerol             
Q.13- Which out of the followings is a fatty acid with 16 carbon atoms and one double bond?
a) Palmitoleic acid
b) Oleic acid
c) Erucic acid
d) Elaidic acid
Q.14-Which out of the followings is an ώ 3 fatty acid?
a) α Linolenic acid
b) Linoleic acid
c) Palmitic acid
d) Arachidonic acid
Q.15- Fats on keeping fora long time under go spontaneous hydrolysis, what is this process called?
a) Saponification
b) Hydrolytic Rancidity
c) Decomposition
d) All of the above
Q.16-  Which out of the following enzymes is deficient  in Gaucher’s disease?    
a) Beta Glucosidase
b) Beta Galactosidase
c) Hexosaminidase A
d) Neuraminidase
Q.17- Prostcyclins are synthesized in- ———?      
a) Platelets   
b) Endothelial cells
c) Gastric mucosa
d) Basophils
Q.18- Cyclo-oxygenase is inhibited by all except——–? 
a) Aspirin
b) Indomethacin
c) Brufen
d) Zileuton
Q.19- The normal level of serum Total cholesterol is———–?
a) 150-220 mg/dl
b) 100-200 mg/dl
c) 1.5-2.5g/dl
d) 20-40 mg/dl
Q.20- Choose out of the followings, a fatty acid with 20 carbon atoms and five double bonds-
a) Timnodonic acid
b) Arachidonic acid
c) Clupanodonic acid
d) Nervonic acid
Q.21- Which type of lipid is a receptor for cholera toxin in the intestine?
a) GM2 Ganglioside
b) GM1Ganglioside
c) Sphingomyelin
d) Galactocerebroside
Q.22- The significance of estimating L: S ratio of amniotic fluid in a pregnant female lies in evaluating-
a) Fetal heart rate                                         
b) Fetal lung maturity
c) Fetal head size
d) Expected date of delivery
Q.23- Iodine number is a measure of-
a) Degree of unsaturation of a fat
b) Degree of rancidity of a fat
c) Measure of volatile fatty acids in a fat
d) Measure of number of –OH groups in a fat
Q.24-Which phospholipid out of the following is antigenic in nature -?     
a) Cardiolipin
b) Lecithin
c) Plasmalogen
d) Cephalin
Q.25- Which out of the followings is not a derived lipid?
a) Ketone body
b) PGE2  
c) Diacylglycerol,
d) Galactosyl ceramide              
Q.26- What are the components of a ceramide?                      
a) Sphingosine+ fatty acid
b) Glycerol+Fatty acids+Phosphoric acid
c) Glycerol+Fatty acids+Phosphoric acid+Nitoregenous base
d) Sphingosine+ fatty acids+Phosphoric acid
Q.27- Choose the incorrect statement-
a) The chemical name of Arachidonic acid is Eicosa penta enoicacid       
b) Cyclo-oxygenase and peroxidase are the components of PG-Hsynthase complex
c) Oleic acid is represented by 18;1,∆9
d) NSAIDs act by inhibiting Phospholipase A2 enzyme.
1-(b)- VLDL
2-(b)- Palmitic acid
3-(d)- Plasmalogen
4-(d) All of the above
5-(d) Stearic acid
6-(c) Phospholipid
7-(c) Arachidonic acid
8-(a) Linoleic acid
9-(a)- Inhibition of cyclo-oxygenase enzyme
10-(a) Choline
11-(b) Bilirubin
12-(c) Glycolipids
13-(a) –Palmitoleic acid
14-(a)-α- Linolenic acid
15-(b)-Hydrolytic Rancidity
16-(a) Beta Glucosidase
17-(b)-Endothelial cells
19-(a) 150-220 mg/dL
20-(a) Timnodonic acid
21-(b) GM1- Ganglioside
22-(b) Fetal lung maturity
23-(a)- Degree of unsaturation
24-(a)- Cardiolipin
25-(a)- Galactosyl Ceramide
26-(a)- Sphingosine+Fatty acid
27-(d) NSAIDs act by inhibiting PhospholipaseA2 enzyme

------------------------------------------ Best Wishes: Dr.Ehab Aboueladab, Tel:01007834123, ------------------------------------------
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