Monday, October 1, 2012

Genetic Basis of Inheritance


11. Turner’s syndrome is characterised by chromosomes
a)46
b)45
c)47
d)48
12. Nucleosome core is made of
a)H1,H2A, H2B and H3
b)H1,H2A, H2B, H3 and H4
c)H1, H2A, H2B, H4
d)H2A, H2B, H3 and H4
13. In human beings 45 chromosomes/single X/XO abnormality causes
a)Down’s syndrome
b)Klinefelter’s syndrome
c)Turner’s syndrome
d)Edward’s syndrome
14. Sex of a child is due to
a)size of ovum
b)Health of father
c)Sex chromosome of father/sperm
d)Sex chromosome of mother/ovum
15. Diploid chromosome number in humans is
a)46
b)44
c)48
d)42
16. In a dihybrid cross, two recessive genes showed 10% recombinants. The distance between two genes is
a)10 map units
b)20 map units
c)30 map units
d)40 map units
17. Sex linked characters are generally
a)Lethal
b)recessive
c)dominant
d)not inherited
18. Trisomy has chromosome complement of
a)2n-1
b)2n-1-1
c)2n+1+1
d)2n+1
19. Muller was awarded Nobel prize in 1946 for his work on
a)Protein synthesis
b)chemistry of nucleic acids
c)cancer
d)X-ray induced mutations
20. Mutations used in agriculture are commonly
a)Induced
b)spontaneous
c)Lethal
d)recessive and lethal
Answer
11B,12D,13C,14C,15A,16A,17B,18D,19D,20A

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Genetic Basis of Inheritance – Competative exam questions Part – 1


1. A cross between homozygous recessive and heterozygous plant is
a)Monohybrid cross
b)Dihybrid cross
c)Test cross
d)Back cross
2. In Red-white flowered cross of Mirabilis jalapa, F2 generation has red, pink and white flowered plants in the ration of
a)1:2:1
b)1:0:1
c)2:1:1
d)1:1:2
3. A blue fowl obtained from mating between black and white fowls, is self-crossed. The F2 ratio is
a)1 black:2 white: 1 blue
b)2 black: 1 white: 1 blue
c)1 black: 2 blue :1white
d)none of these
4. Epistasis in which dihybrid ratio of 9:3:3:1 between Aa Bb ×AaBbis modified is
a)dominance of one allele on another allele at the same locus
b)dominance of one allele on another allele at both its loci
c)interaction of two alleles at different loci
d)interaction between two alleles at same locus
5. Which amino acid is substituted in sickle cell anaemia
a)Glutamic acid by valine in α−chain
b)Glutamic acid by valine in β−chain
c)Valine by glutamic acid in β−chain
d)Valine by glutamic acid in α−chain
6. Mendel found certain traits not ti assort independently. It is due to
a)dominance
b)linkage
c)crossing over
d)amitosis
7. If Mendel had studied 7 traits using a plant with 12 chromosomes instead of 14, he would have
a)discovered incomplete dominance
b)not discovered the law of independent assortment
c)discovered sex linkage d)mapped the chromosome
8. Crossing over in diploid organisms is responsible for
a)Dominance of genes
b)Linkage between genes
c)Recombination of linked genes
d)segregation of alleles
9. Huntington’s chorea appears at the age of
a)25-55 years
b)15-25 years
c)50-60 years
d)10-15 years
10. Persons with Klinefelter’s syndrome have chromosomes
a)XX
b)XY
c)XXY
d)XYY
Answer
1C,2A,3C,4B,5B,6B,7B,8C,9A,10C


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Short question

1.LSD is derived fromArgot fungus
2.Valium is aTranquilliser
3.Psychosis isMental illness
4.BCG is used againstTuberculosis
5.Rh-factor was first discovered inMonkey
6.Myocardial infarction is a disease ofHeart
7.Who received Nobel Prize for peace for his work on wheat and rice?Norman Bourlog
8.Who is the author of ‘Historia Plantarum”Theophrastus
9.A dicot plant without cotyledons is calledDodder Plant (Cuscuta)
10.The branch of biology which deals with identification of disease and its pathogen isPatholog


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Practice

1. The enzyme DNA polymerase can work only in
(A) 3¢ ® 5¢ direction
(B) 5¢ ® 3¢ direction
(C) Both the direction
(D) 5¢ ® 5¢ direction
Answer: (B)
2. Enzyme required for removing RNA primer during DNA replication is
(A) DNA primase
(B) DNA ligase
(C) DNA polymerase I
(D) DNA polymerase III
Answer: (C)
3. During DNA replication, the reunion or recoiling of separated DNA strand is prevented by
(A) Helix destabilizing protein
(B) Single strnad binding protein
(C) Rep protein
(D) Both (A) and (B)
Answer: (D)
4. The enzyme that cuts the bonds of DNA molecule at the origin of replication is
(A) Endonuclease
(B) DNA polymerase
(C) DNA gyrase
(D) DNA ligase
Answer: (A)
5. Which of the following enzyme is required to release the tension imposed by uncoiling of strands?
(A) Endonuclease
(B) DNA ligase
(C) DNA gyrase
(D) DNA helicase
Answer: (C)
6. The cellular composition of m-RNA is
(A) 5-10%
(B) 3-5%
(C) 10-20 %
(D) 70-80%
Answer: (B)
7. Formation of mRNA from DNA is called
(A) Transformation
(B) Transduction
(C) Traslation
(D) Transcription
Answer: (D)
8. The ratio of purines and pyrimidines in mRNA is not 1:1 because the nitrogenous bases are
(A) Unpaired
(B) Paired
(C) Paired only in loops
(D) Paired in stems
Answer: (A)
9. The codons which may present at 3¢ end of mRNA
(A) UAA
(B) UAG
(C) UGA
(D) Any one of these
Answer: (D)
10. Which of the following is not tool of genetic engineering?
(A) Vectors
(B) Enzymes
(C) Foreign DNA
(D) GMO
Answer: (D)


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