Monday, October 22, 2012

Solution to Multiple choice questions- Vitamins


Q.1) The active coenzyme form of Cobalamine is-
a) Methyl cobalamine                                    
b) Deoxyadenosyl cobalamine
c) Both of the above                                    
d) none of the above          
(c)
2) All are one carbon donors except-
a) Serine                                                    
b)S- Adenosyl Methionine
c) Choline                                                    
d)Thiamine                        
(d)
3) All are needed as coenzyme for alpha keto glutarate dehydrogenase complex except-
a) Niacin                                                    
  b)Folic acid
c) Riboflavin                                              
d) Lipoic acid                      
(b)
4) Which of the following vitamins can act without phosphorylation-?
a) Pyridoxine                                              
b) Lipoamide
c) Niacin                                                    
d)Thiamine                        
(b)                      
5)  Impaired Thymidylate formation is due to the deficiency of-
a) Pantothenic acid                                      
b) Niacin
c) Folic acid                                                
d) B12                              
(c)                    
6) Scurvy is due to impaired———— synthesis
a) Collagen                                                
b)Prothrombin
c) Hemoglobin                                            
d) Elastin                            
(a)                            
7) Epileptiform convulsions in infants are found in the deficiency of-
a) Riboflavin                                              
b) Thiamine
c) Niacin                                                    
d)Pyridoxine                    
(d)
8) Pantothenic acid is important for which of the following steps or pathways?
a) Pyruvate carboxylase                              
b)Fatty acid synthesis
c)Gluconeogenesis                                    
d)Glycolysis                      
(b)                  
9) The yellow color of egg yolk is due to the presence of –
a) Riboflavin                                                
b) Thiamine
c) Niacin                                                      
d)Pyridoxine                      
(a)                
10) Neurological manifestations are present in-
a) Dry Beri- Beri                                          
b) B6 deficiency
c) B12 deficiency                                          
d) all of the above            
(d)        
11) Transketolase activity is measured for the detection of————- deficiency
a) Riboflavin                                                
b) Thiamine
c) Niacin                                                    
d)Ascorbic acid              
(b)        
12) All are the synonyms of Folic acid except-
a) Vitamin M                                                
b) Vitamin Bc
c) PGA                                                        
d) Vitamin S                    
(d)        
13)  Schilling test is done to detect the deficiency of-
a) Riboflavin                                              
b) B12
c) Niacin                                                    
d)Biotin                            
(b)          
14) Sub Acute Combined Degeneration of the Spinal Cord is found in the  deficiency of-
a) B12                                                        
b)B6
c) Niacin                                                    
d)Pyridoxine                  
(a)              
15) The Transaminases  require the presence of-
a) Inositol                                                  
b)B6
c) B12                                                        
d)B2                              
(b)                  
16)The active coenzyme form of Vitamin D is-
a) Calcidiol                                                
b) Calcitriol
c) Calcitetrol                                              
d) none of the above        
(b)
17) All are one carbon compounds except-
a) Formyl                                                  
b)Methyl
c) Methylene                                              
d) CO                            
(d)              
18) Which of the following vitamins is an integral component of coenzyme A  that allows two carbon units to enter the TCA cycle?
a) Thiamine                                                
b)Pantothenic acid
c) Biotin                                                      
d)Vitamin A                  
(b)          
19) Sideroblastic anemia occurs due to the deficiency of vitamin-
a) B6                                                          
b)B12
c) B3                                                          
d)B1                              
(a)                      
20)  Homocystinuria is due to the deficiency of-
a)Vitamin B12                                            
b) B6
c) Folic acid                                                
d) All of the above            
(d)
21) Which one of the followings must be utilized during the conversion of Acetyl co A to Malonyl co A
a) Thiamine pyrophosphate                        
b) Acyl carrier protein
c) Biotin                                                    
d)Niacin                        
c)                
22) Wernicke’sEncephalopathy is found in the deficiency of-
a) Riboflavin                                                
b) Thiamine
c) Niacin                                                    
d)Pyridoxine                
(b)
23) Ascorbic acid is required for the utilization of all except-
a) Phenylalanine                                          
b) Tryptophan
c)Tyrosine                                                  
d)Proline                      
(d)            
24) The egg white injury is due to the induced deficiency of –
a) Riboflavin                                                
b) Thiamine
c) Niacin                                                    
d)biotin                        
(d)              
25)  Which of the following statements describing vitamin K is true?
a) Vitamin K is degraded by intestinal bacteria
b) It is obtained by eating citrus fruits
c) It is required for the synthesis of prothrombin              
d) It prevents thrombosis.                                                            
(c)                                                        
26) Intra dermal dye Test is done for the detection of ————-deficiency
a) Riboflavin                                              
b) Thiamine
c) Niacin                                                    
d)Ascorbic acid            
( d)      
27) The Deaminase enzyme requires the presence of-
a) Inositol                                                  
b)B6
c) B12                                                        
d)B2                            
(b)                                            
28)Which vitamin is required for almost all aspects of protein and amino acid metabolism?
a) Vitamin B6                                              
b) Vitamin B12
c) Vitamin C                                                
d) Vitamin B3                
(a)  
29) Which vitamin is required for the absorption of calcium from the gut?
a) Vitamin D                                                
b) Vitamin E
c) Vitamin B12                                            
d)Vitamin K                  
(a)            
30) Out of the followings  which vitamin increases the absorption of iron from the gut?
a) Vitamin D                                                
b) Vitamin E
c) Vitamin C                                                
d)Vitamin K                  
(c)  
31) Which of the following enzymes  does not require a phosphorylated form of coenzyme?
a) Glucose-6-phosphatase                            
b) Pyruvatedehydrogenase
c) Transketolase                                          
d) Transaminase            
(a)
32) Which essential nutrient participates as a coenzyme in the transport of high energy electrons and H+ ions during oxidative phosphorylation in the mitochondrion?
a) Riboflavin                                                
b) Thiamine
c) Niacin                                                    
d)Ascorbic acid            
(a and c)
33) A 2-year- old child presents with chronic cough, bronchitis, growth failure, chronic diarrhea and growth failure. A deficiency of which of the following vitamins should be considered?
a) Vitamin A                                                
b) Vitamin C
c) Vitamin B2                                              
d) Vitamin E                  
(a)                
34) A homeless person is brought in to the emergency room with psychotic illness and smell of alcohol in his breath. Which of the following is needed as part of the treatment?
a) Glucose                                                
b)Niacin
c) Thiamin                                                  
d)Riboflavin                    
(c)
35) The enzyme Ribonucleotide Reductase requires the presence of-
a) Inositol                                                    
b)B1
c) B12                                                        
d)B2                            
(c)                      
36) Signs of vitamin C deficiency include all except-
a) Bruises                                                  
b)Tooth loss
c) Bony fractures                                        
d) Liver failure              
(d)
37) All are signs of niacin deficiency except-
a) Hair loss                                                
b) Diarrhea
c) Dementia                                                
d)Dermatitis                  
(a)
38) Choose the odd one out-
a) Retinol                                                    
b)Ascorbic acid
c) Cholecalciferol                                        
d) Tocopherol                
(b)
39) Deficiency of which of the following vitamins does not cause fatty liver?
a) Vitamin C                                                
b) Vitamin E
c) Cholecalciferol                                        
d) Vitamin A                    
(c)
40) Which out of the following vitamins in PDH complex becomes non functional by Arsenate poisoning?
a) Niacin                                                    
b)Pantothenic acid
c) Lipoamide                                              
d) Riboflavin                  
(c)
41) Excessive consumption of beta-carotene can result in:
a) Toxicity leading to headaches, hair loss and dry skin
b) Renal failure
c) Yellow appearance to the skin
d) Mineralization of soft tissues such as the lungs and kidneys              
(c)
42) Which of the following nutrients, if taken in excess during pregnancy,can cause birth defects?
a) Vitamin A                                                
b)Vitamin C
c) Vitamin D                                                
d)Vitamin E                  
(a)
43) As a hormone, vitamin D has three target tissues. Which are they?
a) Kidney, small intestine, bone                    
b)Heart, blood, bone marrow
c)Kidney, liver, brain                                  
d)Small intestine, liver, fat cells  
(a)
44)  Which of the following vitamins serves an antioxidant function and has a relation to selenium metabolism
a) Vitamin A                                                
b) Vitamin C
c)Vitamin D                                                
d)Vitamin E                    
(d)
45) Which of the following conditions does not rapidly produces a functional deficiency of vitamin K?
a) Warfarin therapy to prevent thrombosis in patients prone to Thrombus formation
b) broad-spectrum antibiotic therapy
c)  Lack of citrus fruit in the diet
d) Premature birth                                                                              
(c)
46) Which one of the followings is a coenzyme, the deficiency of which can cause Folate trap?
a) Methyl Cobalamine                                  
b) Tetrahydrofolate
c) Copper                                                    
d)Biotin                        
(a)
47) A deficiency of which of the following vitamins is associated with neural tube defects-
a) Ascorbic acid                                          
b) Folic acid
c) Nicotinic acid                                          
d)Pantothenic acid            
(b)
48) Which of the following is a coenzyme?
a) Glucose-6-phosphate                              
b) Glucose-1-phosphate
c) Lipoic acid                                              
d) UDP-Glucose            
(c)
49) Which one of the following transfer acyl groups?  
a) Thiamine pyrophosphate                        
b)Lipoamide
c) NADH                                                  
d)FADH2                      
(b)
50) The coenzyme derived from Riboflavin is required by which of the following enzymes?
a) Lactate dehydrogenase                          
b)Glutamate dehydrogenase
c) Acyl co A dehydrogenase                    
d) Malate dehydrogenase
(c)


------------------------------------------ Best Wishes: Dr.Ehab Aboueladab, Tel:01007834123 Email:ehab10f@gmail.com,ehababoueladab@yahoo.com ------------------------------------------
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