Chemistry of lipids

Q.1- Endogenously synthesized triacylglycerols are transported from liver to extra hepatic tissues by which of the followinglipoproteins?

a) Chylomicrons

b) VLDL

c) LDL

d) HDL     

Q.2- All of the followings have 18 carbon atoms except –

a) Linoleic acid

b) Palmitic acid

c) Linolenic acid

d) Stearic acid        

Q.3- Sphingosine is not present in-

a) Cerebrosides

b) Gangliosides

c) sphigomyelin

d) Plasmalogen                         

Q.4- Triacylglycerols are-

a) Energy rich compounds

b) Nonpolar in nature

c) Can be stored in unlimited amounts

d) All of the above           

Q.5- All are essential fatty acids except-              

a)Linoleic,

b) Linolenic

c) Arachidonic acid

d) Stearic acid        

Q.6- The deficiency of Lung surfactant, Dipalmitoyllecithin (DPL) causes, Respiratory Distress Syndrome. DPL is a –

a) Cerebroside

b) Ganglioside

c) Phospholipid

d) Lipoprotein

Q.7- Choose the correct statement

a) The melting point of a fatty acid increases with the increasing degree of unsaturation in the hydrophobic chain

b) Most of the naturally fatty acids have trans double bonds

c) Arachidonic acid is a relatively nonessential fatty acid

d) The membrane lipids are rich in saturated fatty acids.

Q.8- Which out of the following fatty acids is a precursor of series -1 Eicosanoids?

a) Linoleic acid

b) Arachidonic acid

c) Eicosapentaenoic acid

d) Linolenic acid

Q.9- What is the cause of hyper acidity on long-term usage of Aspirin?

a) Inhibition of cyclo oxygenase

b) Increased synthesis of PGs

c) Inhibition of Phospholipase A2

d) All of the above

Q.10- Which nitrogenous base out of the followings is present in lecithin —?

a)Choline

b) Adenine

c) Ethanolamine

d) Any of the above

Q.11- Cholesterol is a precursor of all except-

a)Bile salts,

b)Bilirubin

c) Steroids

d) vitamin D                             

Q.12- Glycerol is used for the synthesis of all except-

a) Glucose.,

b) Phospholipids,

c) Glycolipids,

d) Triacylglycerol             

Q.13- Which out of the followings is a fatty acid with 16 carbon atoms and one double bond?

a) Palmitoleic acid

b) Oleic acid

c) Erucic acid

d) Elaidic acid

Q.14-Which out of the followings is an ώ 3 fatty acid?

a) α Linolenic acid

b) Linoleic acid

c) Palmitic acid

d) Arachidonic acid

Q.15- Fats on keeping fora long time under go spontaneous hydrolysis, what is this process called?

a) Saponification

b) Hydrolytic Rancidity

c) Decomposition

d) All of the above

Q.16-  Which out of the following enzymes is deficient  in Gaucher’s disease?    

a) Beta Glucosidase

b) Beta Galactosidase

c) Hexosaminidase A

d) Neuraminidase

Q.17- Prostcyclins are synthesized in- ———?      

a) Platelets   

b) Endothelial cells

c) Gastric mucosa

d) Basophils

Q.18- Cyclo-oxygenase is inhibited by all except——–? 

a) Aspirin

b) Indomethacin

c) Brufen

d) Zileuton

Q.19- The normal level of serum Total cholesterol is———–?

a) 150-220 mg/dl

b) 100-200 mg/dl

c) 1.5-2.5g/dl

d) 20-40 mg/dl

Q.20- Choose out of the followings, a fatty acid with 20 carbon atoms and five double bonds-

a) Timnodonic acid

b) Arachidonic acid

c) Clupanodonic acid

d) Nervonic acid

Q.21- Which type of lipid is a receptor for cholera toxin in the intestine?

a) GM2 Ganglioside

b) GM1Ganglioside

c) Sphingomyelin

d) Galactocerebroside

Q.22- The significance of estimating L: S ratio of amniotic fluid in a pregnant female lies in evaluating-

a) Fetal heart rate                                         

b) Fetal lung maturity

c) Fetal head size

d) Expected date of delivery

Q.23- Iodine number is a measure of-

a) Degree of unsaturation of a fat

b) Degree of rancidity of a fat

c) Measure of volatile fatty acids in a fat

d) Measure of number of –OH groups in a fat

Q.24-Which phospholipid out of the following is antigenic in nature -?     

a) Cardiolipin

b) Lecithin

c) Plasmalogen

d) Cephalin

Q.25- Which out of the followings is not a derived lipid?

a) Ketone body

b) PGE2  

c) Diacylglycerol,

d) Galactosyl ceramide              

Q.26- What are the components of a ceramide?                      

a) Sphingosine+ fatty acid

b) Glycerol+Fatty acids+Phosphoric acid

c) Glycerol+Fatty acids+Phosphoric acid+Nitoregenous base

d) Sphingosine+ fatty acids+Phosphoric acid

Q.27- Choose the incorrect statement-

a) The chemical name of Arachidonic acid is Eicosa penta enoicacid       

b) Cyclo-oxygenase and peroxidase are the components of PG-Hsynthase complex

c) Oleic acid is represented by 18;1,∆9

d) NSAIDs act by inhibiting Phospholipase A2 enzyme.

 Answers-

1-(b)- VLDL

2-(b)- Palmitic acid

3-(d)- Plasmalogen

4-(d) All of the above

5-(d) Stearic acid

6-(c) Phospholipid

7-(c) Arachidonic acid

8-(a) Linoleic acid

9-(a)- Inhibition of cyclo-oxygenase enzyme

10-(a) Choline

11-(b) Bilirubin

12-(c) Glycolipids

13-(a) –Palmitoleic acid

14-(a)-α- Linolenic acid

15-(b)-Hydrolytic Rancidity

16-(a) Beta Glucosidase

17-(b)-Endothelial cells

18-(d)-Zileuton

19-(a) 150-220 mg/dL

20-(a) Timnodonic acid

21-(b) GM1- Ganglioside

22-(b) Fetal lung maturity

23-(a)- Degree of unsaturation

24-(a)- Cardiolipin

25-(a)- Galactosyl Ceramide

26-(a)- Sphingosine+Fatty acid

27-(d) NSAIDs act by inhibiting PhospholipaseA2 enzyme

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