GRE Biology Practice Test : Cell cycle, Mitosis and Meiosis

1. Nuclear mitosis takes place in

a)Bacteria

b)plants

c)fungi

d)animals

2. In meiosis, all the following statements are true except

a) separation of homologous chromosome in meiosis I

b)prophase is comparatively longer and may take days

c)each bi valent has four chromatids and 2 centromeres

d)centromeres divides only during anaphase I

3. Crossing over takes place only in

a)meiosis only

b)mitosis only

c)both mitosis and meiosis

d)none of the above

4. The following statements are true except

a) chromosomes are single stranded in anaphase of mitosis

b) chromosomes are single stranded in anaphase I of meiosis

c) chromosomes are single stranded in anaphase II of meiosis

d)sister chromatids are separated during anaphase of mitosis

5.Centromeric division takes place during

a) metaphase of mitosis

b)anaphase I of meiosis

c)telophase of mitosis

d)anaphase II of meiosis

6. A cell at G1 of interphase has 8 chromososmes. The number of chromosomes at the anaphase of mitosis will be

a)4

b)8

c)12

d)16

 7. A cell at G1 of interphase has 8 chromososmes. The number of chromatids at the metaphase  of mitosis will be

a)4

b)8

c)12

d)16

8. A cell at G1 of interphase has 8 chromososmes. The number of chromatids at the metaphase I of meiosis will be

a)4

b)8

c)12

d)16

9. A cell at G1 of interphase has 8 chromososmes. The number of chromosomes at the metaphase II of meiosis will be

a)4

b)8

c)12

d)16

10. Exchange of segments between sister chromatids of non homologous chromosome is

a) crossing over

b)transition

c)transversion

d)translocation

11. Which one of the following is not a reason for aneuploidy

a) Robertsonian translocation

b) nondisjuction

c) loss of centromere

d)loss of telomere

12. The most variable phase in cell cycle

a) G1

b)S

c)G2

d)M

13. S phase is characterised by

a) DNA synthesis only

b)histone synthesis only

c) both DNA and histone synthesis

d)none of the above

14. Which of the following statement is true

a) The concentration of cyclins and CDKs varies throughout cell cycle

b)The concentration of CDKs and cyclins remains constant throughout cell cycle

c) The concentration of cyclins remains constant throughout cell cycle

d) The concentration of cyclins varies throughout cell cycle

15. Cyclins and CDKs in M phase

a) CDK4 + cyclin D

b) CDK 2+ cyclin E

c) CDK2+cyclinA

d) CDK 1 +cyclin B/A

16. Cyclin B is involved in the regulation of G2/M checkpoint. What would be the change in the amount of Cyclin B during mitosis

a)Concentration of cyclin B increases

b) Concentration of cyclin B decreases

c)Concentration of cyclin B remains same

d) concentration of cyclin B gradually decreases

17.Growth of cell occurs during which phase of cell cycle?

a) Interphase

b)metaphase

c)anaphase

d)telophase

18. The threadlike structures that radiates from each centromere by the end of prophase are

a) polar microtubules

b) aster microtububules

c) spindle microtubule

d) kinetochore microtubule

19. How many different types of gametes could be produced by an individual with the arbitrary genotype of FFggHHIiJj

a)2

b)4

c)6

d)8

 20. Non-disjunction in meiosis II may result in the formation of 

a) n+1, n-1 and n gametes

b) n+1, n-1 gametes

c)n+2, n-1 and n gametes

d)n+1 gametes only

21.Colchicine arrest cell division during which one of the phases of the cell cycle?

a)G1

b)S

c)Early prophase

d)Metaphase

Answers

1. c)fungi

2. d)centromeres divides only during anaphase I

3. c) both mitosis and meiosis

4. b) chromosomes are single stranded in anaphase I of meiosis

5. d)anaphase II of meiosis

6. c) 16

7. d) 16

8. d) 16

9. a)4

10. d)translocation

11.  d)loss of telomere

12.  a)G1

13. c) both DNA and histone synthesis

14. d) The concentration of cyclins varies throughout cell cycle

15. d) CDK 1 +cyclin B/A

16. d) concentration of cyclin B gradually decreases

17. a) interphase

18. d) kinetochore microtubule

19. b)4

20. a) n+1, n-1 and n gametes

21.  d) Metaphase

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