1)Methyl Malonic aciduria is associated with vitamin B6/ B12 deficiency.
(B12)
2) Glycogen synthesis/ degradation requires Vitamin B6.
(Degradation)
3) Carboxylation/ Decarboxylation reactions require Biotin.
(Carboxylation)
4) In Vitamin B12 deficiency Folate is trapped in the demethylated/methylated form.
(Methylated)
5) The coenzyme form of pyridoxine is Pyridoxal phosphate/Pyridoxol phosphate.
(Pyridoxal phosphate)
6) Hydroxylation/ Dehydrogenation reactions require riboflavin.
(Dehydrogenation)
7) Pellagra is associated with deficiency of B1/ B3.
(B3)
8) The Dehydro/ Hydroxylated form is the active form of ascorbic acid.
(Dehydro)
9) Methotrexate competitively inhibits synthesis of reduced form of Niacin/ Folic acid.
(Folic acid)
10) Xanthurenic acid test is for the assessment of B6/ Folic acid deficiency
(B6 deficiency)
11) Intrinsic factor is required for the absorption of vitamin B6/B12
(B12)
12) Menadione / Menaquinone is a synthetic form of vitamin K
(Menadione)
13) Carboxylation/ Decarboxylation reactions require B6.
((Decarboxylation)
14) The absorbable form of Thiamine is Free Thiamine/TPP
(Free Thiamine)
15) Hydroxylation/ Dehydrogenation reactions require Ascorbic acid.
(Hydroxylation)
16) Pellagra is precipitated by the deficiency of B1/B6.
(B6)
17) The Dehydro/ Reduced form is the active form of Folic acid.
(Reduced)
18) Alcohol inhibits the absorption of Thiamine/vitamin A.
(Thiamine)
19) Histidine loading test is for the assessment of B6/ Folic acid deficiency
(B6)
20) Achlorhydria can cause vitamin B6/ B12 deficiency
(B12)
21) Heme synthesis/ degradation requires VitaminB6
(Synthesis)
22) Carboxylation of Glutamic acid residues requires vitamin K/Biotin during the process of coagulation.
(Vitamin K)
23) Reduction / Dehydrogenation reactions require NADPH
(Reduction)
24) Lactic acidosis is associated with deficiency of B1/ B3.
(B1)
25) “Burning feet syndrome” is a feature of niacin/Pantothenic acid deficiency.
(Pantothenic acid)
26) Sulphonamides competitively inhibit synthesis of Niacin/Folic acid.
(Folic acid)
27) Retinol/ retinoic acid is required for the regulation of gene expression and tissue differentiation.
(Retinoic acid)
28) 11-cisRetinal/11-cis Retinol is required for vision.
(11-cis Retinal)
Q.B- Name the coenzyme for each of the following reactions-
1)Pyruvate——————————->Lactate.
(Niacin-NAD+)
2)Pyruvate——————————–> Oxaloacetate.
(Biotin)
3)Pyruvate———————————>Alanine.
(Pyridoxal phosphate-B6P)
4)Pyruvate———————————>Malate.
(Niacin-NADP+)
5) Lysine————————————->HydroxyLysine.
(VitaminC)
6) Glutamicacid————————->.Gamma Carboxy Glutamic acid
(Vitamin K)
7)Malate Oxaloacetate.
8)Glutamate——————————–>Alpha keto glutarate.
(NAD+ or NADP+)
9) Succinate——————————->Fumarate.
(Riboflavin-FAD)
10)Tyrosine——————————–>Tyramine.
(Pyridoxal phosphate-B6 P)
11)Homocysteine————————> Methionine.
(Vitamin B12 and Folic acid)
12) L- Methyl Malonyl coA————> Succinyl co A.
(Vitamin B12)
------------------------------------------ Best Wishes: Dr.Ehab Aboueladab, Tel:01007834123 Email:ehab10f@gmail.com,ehababoueladab@yahoo.com ------------------------------------------
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