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Abou-Eladab EF

1: Jagannadham MV, Abou-Eladab EF, Kulkarni HM. Identification of outer membrane
proteins from an Antarctic bacterium Pseudomonas syringae Lz4W. Mol Cell
Proteomics. 2011 Jun;10(6):M110.004549. Epub 2011 Mar 29. PubMed PMID: 21447709;
PubMed Central PMCID: PMC3108833.


2: Brandt B, Abou-Eladab EF, Tiedge M, Walzel H. Role of the JNK/c-Jun/AP-1
signaling pathway in galectin-1-induced T-cell death. Cell Death Dis. 2010;1:e23.
PubMed PMID: 21364631; PubMed Central PMCID: PMC3032336.


3: Brandt B, Büchse T, Abou-Eladab EF, Tiedge M, Krause E, Jeschke U, Walzel H.
Galectin-1 induced activation of the apoptotic death-receptor pathway in human
Jurkat T lymphocytes. Histochem Cell Biol. 2008 May;129(5):599-609. Epub 2008 Feb
21. PubMed PMID: 18288482.


4: Walzel H, Fahmi AA, Eldesouky MA, Abou-Eladab EF, Waitz G, Brock J, Tiedge M.
Effects of N-glycan processing inhibitors on signaling events and induction of
apoptosis in galectin-1-stimulated Jurkat T lymphocytes. Glycobiology. 2006
Dec;16(12):1262-71. Epub 2006 Aug 17. PubMed PMID: 16917081.



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Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytes

Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytes
B Brandt, T Büchse, EF Abou-Eladab, M Tiedge, E Krause, U Jeschke, H Walzel
Histochemistry and cell biology 129 (5), 599-609


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Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytes

Title
Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytes
Authors
Bettina Brandt, Tom Büchse, Ehab Fathi Abou-Eladab, Markus Tiedge, Eberhard Krause, Udo Jeschke, Hermann Walzel
Publication date
2008/5/1
Journal name
Histochemistry and cell biology
Volume
129
Issue
5
Pages
599-609
Publisher
Springer Berlin/Heidelberg
Description
Abstract Galectin-1 (gal-1), a member of the family of ?-galactoside binding proteins,
participates in several biological processes such as immunomodulation, cell adhesion,
regulation of cell growth and apoptosis. The aim of this study was to investigate whether gal-
1 interferes with the Fas (Apo-1/CD95)-associated apoptosis cascade in the T-cell lines
Jurkat and MOLT-4. Gal-1 and an Apo-1 monoclonal antibody (mAb) induced DNA-
fragmentation in Jurkat T-cells whereas MOLT-4 cells were resistant. Gal-1 stimulated ...


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Aminoacids-ehab10f

*1.Aminoacids are*

 a) building blocks of carbohydrates

b) building blocks of nucleic acids

 c) building blocks of lipids

d) building blocks of proteins

*2. Amino acids has*

 a) both amino group and carboxyl group

b) both amino group and keto group

c) amino group only

d) carboxyl group only

*3. The simplest amino acid is*

a) Proline

b) methionine

c) glycine

d) serine

*4. Which of the following amino acid is alpha-helix terminator

a) tryptophan

b) phenyl alnine

c) tyrosine

d) proline

*5. The first amino acid in a polypeptide chain is*

 a) Serine

b) Valine

c) Alanine

d) Methionine

*6. Which of the following amino acid has buffering capacity*

 a) Tryptophan

b) cysteine

c) histidine

d) arginine

*7. Which of the following is an imino acid*

a) serene

b) threonine

c) valine

d) proline

*8. The naturally occurring form of amino acid in proteins

* a) L-amino acids only

b) D-amino acids only

c) both L and D amino acids

d) none of these

*9. Sulphur containing amino acids are*

a) Cysteine and methionine

b) Methionine and threonine

c) Cysteine and threonine

d) Cysteine and serine

 *10. Aromatic amino acids include*

a) Phenylalanine, tyrosine and tryptophan

b) Phenylalanine, serine and tryptophan

c) Threonine, tyrosine and tryptophan

d) Asparagine, tyrosine and tryptophan

*11. Positively charged basic amino acids are*

 a) Lysine and arginine

 b) Lysine and asparagine

c) Glutamine and arginine

d) Lysine and glutamine

*12. Acidic amino acids include*

a) Arginine and glutamate

b) Aspartate and asparagine

c) Aspartate and lysine

d) Aspartate and glutamate

*13. Amino acids with hydroxyl groups are*

 a) serine and alanine

b) Alanine and valine

c) serine and threonine

d) Valine and isoleucine

*14. Absorbance at 280nm exhibited by protein is due to *

a) aliphatic amino acids

b) all amino acids

c) Non-polar amino acids

d) aromatic amino acids

* * *Answers* *

1-d*

*2-a*

*3-c*

 *4-d*

 *5-d*

 *6-c*

 *7-d*

*8-a*

 *9-a*

*10-a*

 *11-a*

 *12-d*

*13-c*

 *14-d* 

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carbohydrate-ehab10f

*1*.*The most abundant bio molecule on the earth *

a) Nucleic acids

b) proteins

c) lipids

d) carbohydrates

*2. The major functions of carbohydrates

a) structural framework

b) storage

c) both a and b

d) none of these

*3. The general formula of carbohydrate is*

a) (CH2O)n

b) (C4H2O)n

c) (C6H2O)n

d) (C2H2O)n COOH

*4. Carbohydrates are *

a) polyhydroxy aldehydes and phenols

b) polyhydroxy aldehydes and ketones

c) polyhydroxy ketones and phenols

d) polyhydroxy phenols and alcohols

*5. Structural polysaccharides include*

a) cellulose, hemicellulose and chitin

b) cellulose, starch and chitin

c) cellulose, starch and glycogen

d) cellulose, glycogen and chitin

*6. Nutritional polysaccharides are*

a) starch and glycogen

b) starch and chitin

c) starch and cellulose

d) starch and glucose

*7. Glycogen in animals are stored in  *

a) liver and spleen

b) liver and muscles

c) liver and bile

d) liver and adipose tissue

*8. Carbohydrates accounts*

a) 30% in plants and 20% in animals

b) 30% in plants and 10% in animals

c) 30% in plants and 1% in animals

d) 50% in plants and 50% in animals

*9. Smallest carbohydrates are trioses. Which of the following is a triose?*

a) glucose

b) ribulose

c) ribose

d) glyceraldehyde

*10. Which of the following is a reducing sugar

a) glucose

b) dihydroxyacetone

c) erythulose

d) none of these

*11. Oligosaccharides linked to proteins are called *

a) glycoproteins

b) glycolipids

c) galactosides

d) ganglioside

*12. In polysaccharides, monosaccharaides are joined by*

a) peptide bond

b) glucose bond

c) glycosidic bond

d) covalent bond

*13. Sucrose is a *

a) monosaccharide

b) disaccharide

c) polysaccharide

d) triose**

*14. Lactose is a disaccharide consists of*

a) glucose and fructose

b) glucose and galactose

c) glucose and sucrose

d) glucose and ribose

*15. In lactose, the linkage is*

a) β-1-4 linkage

b) β-1-2 linkage

c) α-1-4 linkage

d) α-1-2 linkage

*15. Maltose is a disaccharide consists of*

a) glucose and fructose

b) glucose and galactose

c) glucose and sucrose

d) glucose and glucose

*16. In maltose, the linkage is*

a) β-1-4 linkage

b) β-1-2 linkage

c) α-1-4 linkage

d) α-1-2 linkage

*17. Starch consists of *

a) unbranched amylose and branched amylopectin

b) branched amylose and branched amylopectin

c) unbranched amylose and unbranched amylopectin

d) none of these

*18. Cellulose is made up of repeating units of*

a) β-1-4 linkage between D-glucose units

b) β-1-2 linkage between D-glucose units

c) α-1-4 linkage between D-glucose units

d) α-1-2 linkage between D-glucose units

*19. Amylopectin has*

a) β-1-4 and β-1-6 linkage

b) β-1-2 linkage

c) α-1-4 and α-1-6 linkage

d) α-1-2 linkage

*20. Chitin consists of*

a) N-acetyl muramic acid

b) N-acetyl glucosamine

c) D-glucose units

d) N-acetyl muramic acid and N-acetyl glucosamine

*Answers*

*1-d*

*2-c*

*3-a*

*4-b*

*5-a*

*6-a*

           

*7-a*

*8-c*

*9-d*

*10-a*

*11-a*

*12-c*

*13-b*

*14-b*

*15-d*

*16-c*

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